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Job Summary
The Genetics and Aging Research Unit (GARU) in the Charlestown Navy Yard is seeking a full-time Research Technician I to carry out cell culture experiments, wet lab research, animal work, basic molecular biology, genetic analysis, and lab managerial duties. The GARU is a collection of multidisciplinary laboratories with varied specialties all collaborating to seek a better understanding of the molecular underpinnings of Alzheimer’s disease and discover novel avenues of treatment.The candidate will work directly with Dr. Luisa Quinti, to identify potential drugs that modulate neuroinflammation and novel therapeutic strategies for enhancing clearance of the aggregation-prone amyloid beta peptide in Alzheimer's disease. The candidate will perform several experiments and assays, such as drug treatments of microglial cells, amyloid beta uptake and degradation by microglia, secretion of pro-inflammatory cytokines and M1/M2 activation of microglial cells. The project will include experiments using mammalian cell culture approach, enzyme-linked immunosorbent assay (ELISA), SDS-PAGE, Western blotting, fluorescence microscopy and high-throughput imaging. The candidate is expected to show a high degree of interest in the project, self-motivation, initiative and attention to details.
Responsible for maintaining laboratory equipment, organizing and preparing samples, conducting experiments, and recording and analyzing data.
Candidates who are in the process of completing their bachelor's degree have a grace period of six months from their hire date (up to 1 year if starting per diem) to provide degree equivalency verification.
Does this position require Patient Care? No
Essential Functions:
-Perform laboratory experiments following established protocols and procedures.
-Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
-Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
-Record experimental data accurately and maintain organized records of procedures, protocols, and results.
-Compile and analyze data using appropriate statistical and analytical methods.
-Assist in data interpretation and presentation, contributing to research findings and reports.
Qualifications
Education
High School Diploma or Equivalent required and Bachelor's Degree Biology preferred
Candidates who are in the process of completing their bachelor's degree have a grace period of six months from their hire date (up to 1 year if starting per diem) to provide degree equivalency verification.
Can this role accept experience in lieu of a degree? Yes
Licenses and Credentials:
Experience:
Prior laboratory experience, either through academic coursework, internships, or employment 1-2 years preferred
Knowledge, Skills and Abilities:
- Strong theoretical and practical knowledge of laboratory techniques and procedures.
- Familiarity with common laboratory equipment and instruments used in research experiments.
- Proficiency in data collection, analysis, and scientific software tools.
- Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
- Strong problem-solving skills and the ability to troubleshoot technical issues.
- Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.
Additional Job Details (if applicable)
The primary responsibility is technical experimental support for the multiple ongoing projects in the lab. The successful candidate will be responsible for carrying out research experiments plus all related job duties as assigned. Duties may include:
Protein biochemistry experiments using gel electrophoresis, western blot analysis, ELISA, and immunoprecipitation techniquesMolecular biology experiments including DNA extraction, PCR, DNA-gel electrophoresisMicroscopy experiments including tissue sectioning, immunocytochemistry, and fluorescence confocal microscopyMaintaining cell culturesMaintenance, management, treatments, and surgeries on mice and mice coloniesPreparing lab reagents, chemicals, instruments and equipmentPerform independent literature searchesAssist with analyzing data and interpreting resultsAssist the PI(s) with determining the most suitable methodologyPerform basic design and modification of protocolsCalculate, transcribe and analyze dataPrepare and present reportsOrganize and summarize acquired data, using scientific and statistical techniquesOrganize and/or draft material for the preparation of research papers, manuscripts and other documents for publication and/or presentationParticipate in the design of experiments
Remote Type
Onsite
Work Location
114 16th Street
Scheduled Weekly Hours
40
Employee Type
Regular
Work Shift
Day (United States of America)
EEO Statement:
The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.