Job Title: Temporary Scientist II
Location: Alameda, California, 94502 (Onsite)
Schedule: Monday – Friday
Type: Contract 

Overview

We are seeking a highly motivated and detail-oriented Scientist II to join our Drug Discovery Sciences team. This position through Joule will support the discovery of anti-cancer agents through the application of advanced LC-MS/MS techniques. The ideal candidate has strong technical expertise in bioanalysis and a background in pharmacokinetics, with the ability to work independently and collaboratively in a fast-paced research environment.

Key Responsibilities

Perform LC-MS/MS analysis of small molecules in biological matrices to support PK, TK, PD, and efficacy studies.

Conduct in vitro ADME studies (e.g., microsomal stability, protein binding, hepatocyte incubation).

Maintain and troubleshoot mass spectrometry instrumentation for optimal performance.

Prepare clear, concise reports and present findings to project teams.

Qualifications

Bachelor’s degree in a related field with 2–5 years of experience, or Master’s degree with at least 1 year of relevant experience.

Hands-on experience with LC-MS/MS, HRMS, and sample extraction in matrices such as plasma and tissues.

Proficient with Phoenix WinNonlin and LC-MS data analysis software (Sciex Analyst, Agilent MassHunter, etc.).

Knowledge of peptide LC-MS analysis and experience with RapidFire/QTOF or QTRAP systems is a plus.

Strong communication, organizational, and problem-solving skills; ability to multitask across projects

 

Ref: #568-Clinical

System One, and its subsidiaries including Joulé, ALTA IT Services, TeamPeople, and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.